BROMOBENZENE-INDUCED CLARA CELL DAMAGE: THE CONTRIBUTION OF CYTOCHROME P-450 SYSTEM LOCALIZED IN THE CLARA CELL
نویسندگان
چکیده
منابع مشابه
[The Clara cell].
Smith, P., Heath, D., and Moosavi, H. (1974). Thorax, 29, 147-163. The Clara cell. The ultrastructure of the bronchiolar Clara cell was examined in normal adult and neonatal rats, in similar animals which had been acutely exposed to hypoxia, and in adult rats following repeated doses of the anorexigen chlorphentermine. The Clara cell has all the features of a secretory cell, the product of secr...
متن کاملThe Clara cell.
Smith, P., Heath, D., and Moosavi, H. (1974). Thorax, 29, 147-163. The Clara cell. The ultrastructure of the bronchiolar Clara cell was examined in normal adult and neonatal rats, in similar animals which had been acutely exposed to hypoxia, and in adult rats following repeated doses of the anorexigen chlorphentermine. The Clara cell has all the features of a secretory cell, the product of secr...
متن کاملClara cell protein as a marker of Clara cell damage and bronchoalveolar blood barrier permeability.
The 16 kDa Clara cell protein (CC16), an abundant component of airway secretions, has recently been proposed in humans as a pulmonary marker measurable not only in bronchoalveolar lavage fluid (BALF) but also in serum. The aim of the present study was to investigate the changes and determinants of CC16 concentrations in these fluids in normal rats and rats with lung injury. Female Sprague-Dawle...
متن کاملPulmonary cytochrome P450 monooxygenase and Clara cell differentiation in mice.
Various studies indicate that cytodifferentiation of Clara cells and development of pulmonary cytochrome P450 (CYP) monooxygenases occur postnatally. The timing of these events is species-specific. Neonatal mice are more susceptible than adult mice are to Clara cell injury by naphthalene, but little is known about the postnatal development of Clara cells and CYP in mice. This study was designed...
متن کاملThe Clara cell: a "Third Reich eponym"?
German anatomist Max Clara (1899-1966) described the "Clara cell" of the bronchiolar epithelium in 1937. The present article investigates Clara's relationship with National Socialism, as well as his use of tissue from executed prisoners for research purposes, details about both of which are largely unknown to date. Our methodology for the present study focussed on analysis of material from hist...
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ژورنال
عنوان ژورنال: Journal of Toxicologic Pathology
سال: 1990
ISSN: 0914-9198,1881-915X
DOI: 10.1293/tox.3.223